Premature Ejaculation Medication: Priligy — Are You Using It Correctly?
Previously, we introduced the advantages of Priligy (dapoxetine hydrochloride) as a medication for premature ejaculation (PE). Recently, many patients have asked:
“Is Priligy a treatment medication? How should it be taken correctly?”
The right approach allows men to fully experience pleasure and intimacy during sexual activity. Medication also requires the “correct method” of use. This article will answer common questions about the proper use of Priligy.
Is Priligy a treatment medication?
Priligy is currently the only medication specifically approved for the treatment of premature ejaculation in many countries. It is a selective serotonin reuptake inhibitor (SSRI) designed for PE management.
Its advantages include:
Rapid absorption
Fast onset of action
Short half-life
Rapid elimination from the body, reducing the risk of accumulation
These pharmacological characteristics make Priligy a commonly used option for on-demand treatment of premature ejaculation.

Are you using your “premature ejaculation medication” correctly?
Suitable patients
Priligy is intended for adult men aged 18–64 years with premature ejaculation who meet all of the following criteria:
① Rapid ejaculation with minimal stimulation
Ejaculation occurs persistently or repeatedly with very little sexual stimulation:
Before penetration
During penetration
Shortly after penetration
and before the individual wishes it to happen.
② Significant personal distress or relationship problems
Premature ejaculation causes noticeable emotional distress or difficulties in intimate relationships.
③ Poor control over ejaculation
The individual has difficulty delaying or controlling ejaculation.
Dosage and administration
Priligy is an on-demand oral medication.
The tablet should be swallowed whole with more than 250 ml of water.
Recommended dosage:
The recommended starting dose is 30 mg (one tablet).
If the effect is insufficient after taking 30 mg and side effects are acceptable, the dose may be increased to the maximum recommended dose of 60 mg.
The maximum recommended frequency is once every 24 hours.
Priligy is a prescription medication and should be purchased and used according to medical advice.
After starting treatment, doctors generally evaluate the balance between risks and benefits:
After the first 4 weeks of treatment
Or after 6 treatment doses
to decide whether continued use is appropriate.
When should Priligy be taken?
Priligy should generally be taken 1–3 hours before sexual activity.
This is because drug metabolism varies significantly between individuals. Taking it too early or too late may result in reduced effectiveness for some users.
When prescribing Priligy, doctors may provide enough tablets for several attempts so patients can identify the timing that works best for them.
If the first dose does not produce the expected effect, do not immediately conclude that the medication does not work. Instead, try adjusting the timing of administration (under medical guidance) to determine the optimal time for effectiveness.
Possible side effects
Side effects are more common during the first 4 weeks of treatment, especially after the first dose.
The most frequently reported reactions involve the digestive and nervous systems, including:
Nausea
Diarrhea
Headache
Dizziness
Insomnia
Sexual dysfunction and discontinuation symptoms occur at relatively low rates.
In most cases, side effects are mild and can be tolerated by many patients.
Does Priligy really work?
The answer is: Clinical studies have shown that Priligy can help improve premature ejaculation symptoms in many patients.
Priligy has pharmacokinetic characteristics that make it suitable for on-demand treatment:
It reaches peak blood concentration relatively quickly (Tmax approximately 1.3 hours).
It has a relatively short terminal half-life (approximately 19 hours).
Clinical studies involving thousands of patients in Europe and other countries have evaluated dapoxetine for premature ejaculation.
After 12 weeks of treatment, studies reported:
Average intravaginal ejaculatory latency time (IELT) increased approximately 2.5–3 times
Sexual satisfaction scores improved by approximately 22.9%–27.8%
According to research by Jian BP et al., the reported effectiveness rate was:
Approximately 70.4% after 4 weeks
Approximately 74.6% at the final follow-up
Important note: Priligy (dapoxetine) is a prescription medication. It is not suitable for everyone, and people with certain medical conditions or those taking specific medications should consult a healthcare professional before use.